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BlasTine Tablet
Pack Image（https://medex.com.bd/storage/images/packaging/blastine-20-mg-tablet-3208649522-ybXEowSTMa.webp）
Bilastine（https://medex.com.bd/generics/1457/bilastine）
20 mg
Jayson Pharmaceutical Ltd.（https://medex.com.bd/companies/37/jayson-pharmaceutical-ltd/brands）
Unit Price:
৳ 10.00
(3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Alternate Brands（https://medex.com.bd/generics/1457/bilastine/brand-names）
Innovator's Monograph
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Innovator's Monograph for Bilastine
20 mg Tablet（https://medex.com.bd/attachments/mfEPBDDHGXxD3TJlPOI0Bw3eGy6SAL/bilastine-20-mg-tablet-prescribing-information） 10 mg ODT（https://medex.com.bd/attachments/LtA8NIgRzzL2kOSDXpXBioOV6ToO8P/bilastine-10-mg-odt-prescribing-information）
বাংলায় দেখুন（https://medex.com.bd/brands/40036/blastine-20-mg-tablet/bn）
Indications
BlasTine is indicated for the symptomatic treatment of-
Allergic rhino conjunctivitis (seasonal and perennial) and
Urticaria
BlasTine is also used to relieve the symptoms of hay fever (sneezing, itchy, runny, blocked-nose and red and watery eyes).
* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন（https://medex.com.bd/news/104/danger-of-taking-medication-without-doctors-advice）'
Pharmacology
Bilastine is a potent, effective, non-sedating, long-acting histamine antagonist with selective & high affinity to H1 receptor (3 times higher than Cetirizine and 5 times higher than Fexofenadine). Even at a high concentration, Bilastine does not show affinity for the 30 other receptors including muscarinic, serotonergic, dopaminergic and noradrenergic receptors, for the other histamine receptor subtypes (H2, H3 and H4). It shows excellent safety profile and very favorable pharmacokinetic characteristics. Bilastine doesn’t undergo any metabolism to be active. Bilastine is excreted by feces (non -systemic) & urine (systemic) approximately 66.35% & 28.31% respectively.
Dosage & Administration
Adults & adolescents (12 years of age and over) : 20 mg tablet once daily for symptomatic relief of allergic rhinitis, urticaria and allergic rhinoconjunctivitis. The maximum recommended daily dose is 20 mg Bilastine (1 tablet) and should not be exceeded. If a dose is missed, the next scheduled dose should be taken. An extra dose should not be taken. 20 mg Bilastine tablet (1 tablet) once daily should be swallowed with water on an empty stomach to achieve optimal exposure to Bilastine.
Children between 6 to 11 years : 10 mg mouth dissolving tablet for the symptomatic relief of allergic rhinitis, allergic rhinoconjunctivitis and urticaria. The Mouth dissolving tablet is for oral use only. It should be placed in the mouth. It will disperse rapidly in saliva and can be easily swallowed. Alternatively, the mouth dissolving tablet can be dispersed in a tea spoon of water before being swallowed by the children. The maximum recommended daily dose for children in between 6 to 11 years is 10 mg Bilastine mouth dissolving tablet (1 tablet) and should not be exceeded. If a dose is missed, the next scheduled dose should be taken. An extra dose should not be taken.
Children between 2 to 11 years : 4 ml once daily.
* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন（https://medex.com.bd/news/104/danger-of-taking-medication-without-doctors-advice）'
Interaction
Concomitant use of BlasTine with ketoconazole, erythromycin, cyclosporine or diltiazem increases the concentration of BlasTine. But these changes do not appear to affect the safety profile of any of the drugs. Intake of alcohol and 20 mg BlasTine shows same psychomotor performance similar to that of alcohol and placebo. Concomitant intake of BlasTine 20 mg and lorazepam 3 mg for 8 days did not potentiate the depressant CNS effects of lorazepam.
Contraindications
Bilastine is contraindicated in patients with hypersensitivity to the active substance or to any of the excipients of the tablet.